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一抗

載脂蛋白L4抗體

文字:[大][中][小] 2017-5-4    瀏覽次數(shù):1591    

                                                       載脂蛋白L4抗體                                                                                                                                                
英文名稱(chēng)  Anti-APOL4/Apolipoprotein L4 
中文名稱(chēng)  載脂蛋白L4抗體 
別    名  APOL IV; ApoL-IV; APOL4; APOL4_HUMAN; Apolipoprotein L IV; Apolipoprotein L-IV; Apolipoprotein L4; APOLIV; CTA 212A2.2; OTTHUMP00000028937. 

詳細(xì)介紹:


濃    度  1mg/1ml 
規(guī) 格  0.2ml/200μg   
抗體來(lái)源  Rabbit  
克隆類(lèi)型  polyclonal 
交叉反應(yīng)  Human   
產(chǎn)品類(lèi)型  一抗    
研究領(lǐng)域  心血管 細(xì)胞生物  
蛋白分子量  predicted molecular weight: 37kDa 
性    狀  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human APOL4/Apolipoprotein L4 
亞    型  IgG 
純化方法  affinity purified by Protein A 
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
(石蠟切片需做抗原修復(fù)) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

相關(guān)資料:


產(chǎn)品介紹 The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-IV (apolipoprotein L-IV), also known as APOL4, is a 351 amino acid protein that exists as multiple alternatively spliced isoforms, one of which is secreted. Expressed in spleen, placenta, spinal cord, uterus, testis and trachea, apoL-IV is thought to play a role in lipid exchange and transport throughout the body and may be involved in reverse cholesterol transport, specifically from peripheral cells to the liver. Overexpression of apoL-IV is associated with schizophrenia, suggesting that apoL-IV may play a role in the pathogenesis of neural disorders.
Function : May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Subcellular Location : Secreted.
Tissue Specificity : Widely expressed; the highest levels are in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis; levels are low in brain, heart and pancreas.
Similarity : Belongs to the apolipoprotein L family.
Database links : UniProtKB/Swiss-Prot: Q9BPW4.3

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