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英文名稱 Anti-BNP(H1G3)
中文名稱： 人腦鈉素單克隆抗體
別 名 BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein.
濃 度 1mg/1ml
規 格 0.1ml/100μg 0.2ml/200μg
抗體來源 Mouse
克隆類型 monoclonal
克 隆 號 H1G3
交叉反應 Human
產品類型 一抗
研究領域 心血管 免疫學
蛋白分子量 predicted molecular weight: 14kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BNP
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
腦鈉素主要是心臟激素，心臟作為內分泌器官釋放腦鈉素，調解體液及電解質內環境的恒定性。 B型利鈉肽（鈉尿肽）（B－typenatriureticpeptide，BNP），又稱腦鈉素或腦鈉肽，因其有排鈉利尿、內皮非依賴性的血管平滑肌作用而具有降壓、抗心肌纖維化、影響神經內分泌系統等功效。近來發現BNP在各種心血管疾病，尤其是心室功能不全、急性心肌梗死（ami）、高血壓等疾病的診斷、治療及預后等方面有重要意義，已引起臨床工作者的高度重視。
中文名稱： 人腦鈉素單克隆抗體
別 名 BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein.
詳細介紹：
濃 度 1mg/1ml
規 格 0.1ml/100μg 0.2ml/200μg
抗體來源 Mouse
克隆類型 monoclonal
克 隆 號 H1G3
交叉反應 Human
產品類型 一抗
研究領域 心血管 免疫學
蛋白分子量 predicted molecular weight: 14kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BNP
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資料：
產品介紹 Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
腦鈉素主要是心臟激素，心臟作為內分泌器官釋放腦鈉素，調解體液及電解質內環境的恒定性。 B型利鈉肽（鈉尿肽）（B－typenatriureticpeptide，BNP），又稱腦鈉素或腦鈉肽，因其有排鈉利尿、內皮非依賴性的血管平滑肌作用而具有降壓、抗心肌纖維化、影響神經內分泌系統等功效。近來發現BNP在各種心血管疾病，尤其是心室功能不全、急性心肌梗死（ami）、高血壓等疾病的診斷、治療及預后等方面有重要意義，已引起臨床工作者的高度重視。
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